May 21, 2017

Erythritol a Marker for Weight Gain

I have long suspected that many of the sugar substitutes were overrated. Now the word is out on one of them, sugar alcohol erythritol. This commonly used sugar replacement used in low-calorie foods that people eat to lose weight may actually have the opposite effect.

The sugar alcohol erythritol occurs naturally in foods like pears and watermelons but has been used as a sugar replacement in low-calorie foods. It is found in the sugar replacement products Zsweet, Zero and Sweet Simplicity. Truvia is a mix of erythritol and stevia.

The study was a collaboration of researchers at Cornell, Braunschweig University of Technology in Germany and the University of Luxembourg, on a discovery-based analysis to identify metabolomic markers linked to weight gain and increased fat mass in students transitioning to college life.

"About 75 percent of this population experiences weight gain during the transition," Patricia Cassano, professor in the Division of Nutritional Sciences at Cornell, said in a press release. "With this in mind, it is important to identify biomarkers of risk that could guide its understanding and prevention."

Researchers found that people who gained weight and abdominal fat over the course of a year had 15 times higher blood erythritol at the beginning of the year compared to those who were stable or had lost weight and fat mass.

The study was part of Cornell's ENHANCE project by the Division of Nutritional Sciences to understand how the transition to college affects changes in diet, weight and metabolism in students.

"With the finding of a previously unrecognized metabolism of glucose to erythritol and given the erythritol-weight gain association, further research is needed to understand whether and how this pathway contributes to weight-gain risk," Cassano said.

2 comments:

Gretchen said...

I think we need to distinguish dietary erythritol with endogenously produced. Here's an old article on dietary erythritol and blood levels:

http://www.sciencedirect.com/science/article/pii/S0273230096901099?via%3Dihub

It's possible the high levels they found in the blood were the result of a metabolic adnormality, not a cause.

I confess I didn't read the whole article you refer to. Did they discuss this?

Bob Fenton said...

Cannot find any reference that would suggest they distinguished dietary with endogenously produced. In looking at the information I received, all discussion seems centered on dietary erythritol.