This is a continuation of the previous
blog.
Activity:
Light activity - Light activity
can have a surprising glucose-lowering effect. Walking could be
considered light exercise.
High-intensity and moderate
exercise - Please read my blog on safe blood glucose levels for
exercising. Also talk with your doctor before beginning exercise
that fits in this category.
Exercise is often described as
something that always lowers blood glucose; however, high-intensity
exercise, such as sprinting or weight lifting, can sometimes raise
blood glucose. This stems from the adrenaline response, which tells
the body to release stored glucose. But this is not a reason to
avoid high intensity exercise – studies show it can improve blood
glucose for one to three days post-exercise! Please note that in
some cases high-intensity exercise can also drop blood glucose very
rapidly (2-3 mg/dl per minute), especially if you are taking insulin.
This also happens to many people on oral medications until they have
been exercising for a couple of weeks or longer. The best way to see
how individual exercise sessions affect your blood glucose is to test
prior and after exercise.
Biological:
Dawn phenomenon - The “dawn
phenomenon” normally occurs in people with type 2 diabetes. The
term refers to the body’s daily production of hormones around wake
up time. During this time, the body makes less insulin and produces
more glucagon, which raises blood glucose. The best way to figure
out how dawn phenomenon affects you is to wear a CGM or wake up and
test your blood glucose early in the morning. Not everyone
experiences dawn phenomenon, but it is common for about 50 percent of
type 2 patients on oral medications,
Scar tissue and lipodystrophy –
If you are taking oral medications only, this will not affect you.
Using the same sites on the body for injections sights can lead to
lipodystrophy and scar tissue buildup. These result in erratic
absorption of insulin, leading to glycemic variability and making it
harder to spend more time in range. To avoid these issues, rotate
your injection sites and don't reuse needles.
Insufficient Sleep - In my
experience, I have found that I need more insulin on days following
less than seven hours of sleep. The highest blood glucose of the day
is even higher on days following little sleep. These findings are
consistent with many studies, which have found that not getting
enough sleep leads to worse diabetes management, insulin resistance,
weight gain, and increased food intake.
Stress and illness - Stress and
illness can cause the body to release epinephrine (adrenaline),
glucagon, growth hormone, and cortisol. As a result, more glucose is
released from the liver (glucagon, adrenaline) and the body can
become less sensitive to insulin (growth hormone, cortisol). In some
cases, people are much more insulin sensitive right before getting
sick and can tend to run low blood sugars.
Allergies – Research did not
yield any results and apparently is not worthy of study. I do have one
friend that suffers from ragweed allergy and has problems with his
blood glucose levels during ragweed pollen season.
A higher glucose level
(“glucotoxicity”) - Hyperglycemia can lead to a state known
as “glucotoxicity,” which can actually cause insulin resistance.
People going on insulin after being on oral medications can
experience this and spend a few days up to two weeks adjusting
insulin to bring this under management.
Periods (Menstruation) - There
is not an easy answer to the question of how periods affect women’s
blood sugars. Many women report having higher blood sugar levels a
few days prior to their period starting, but some women notice a
sharp drop in sugar levels. To figure out how you respond, your best
bet is to test your blood glucose often during this time of month.
Smoking - Some studies suggest
that smoking can increase insulin resistance, and people with
diabetes who smoke are more likely than nonsmokers to have trouble
with insulin dosing and managing their diabetes. Smokers also have
higher risks for serious complications.
Environmental:
Medication or insulin that has gone
bad – Some people stop taking oral medications and when they
need to restart, use the old medications, and get little or no help.
Others ruin their insulin by exposing it to direct sunlight or
leaving it in the car on a hot day. The worst part is that it’s
hard to know if it has actually gone bad unless you try a new vial.
In addition, the insulin may work unpredictably. Unopened insulin
should be stored in a refrigerator at approximately 36-46 °F.
According to the FDA, insulin can be left unrefrigerated at a
temperature from 59-86 °F for up to 28 days.
An accurate blood glucose reading
- While this seems fairly obvious, I occasionally find myself testing
multiple times in a row, since I do not believe the initial value.
In some cases, the second time I get a much lower value, and it’s
because I failed to wash my hands. I suggest retesting if you don’t
believe the value on the meter.
Altitude – People on oral
medications generally notice little difference with being at higher
or even lower altitude. People using insulin need to be careful as
insulin resistance can increase insulin needs. Others that are
climbing or skiing may need less insulin. Testing more frequently
may be a necessity.
To the above and the previous blog, I
would be remiss if I did not mention attitude. A positive attitude
makes diabetes management easier and helps make diabetes burnout and
mild depression easier to conquer. Then add developing good habits
that become part of a daily routine and burnout seldom happens.
Another blog about the reasons for variability of blood glucose levels is this one. There are overlaps with the ideas included in the blog from yesterday and this blog of today.
Another blog about the reasons for variability of blood glucose levels is this one. There are overlaps with the ideas included in the blog from yesterday and this blog of today.