Overactive bladder (OAB) is a condition
that about 16 percent of the American adult population has; however,
the actual percent is unknown. OAB is a condition defined by a group
of urinary symptoms related to the control and frequency of
urination. Overactivity of a muscle in the bladder wall is
considered to be the main cause of OAB. Stimulants like caffeine and
alcohol can also cause symptoms.
Causes - A
variety of physical conditions and lifestyle habits can influence the
chances of developing OAB. It is often the result of a combination
of factors where no single cause may be determined. Within the body,
OAB is often the result of spasms in the detrusor muscle, the main
muscle of the urinary bladder wall.
When the brain senses the bladder is
about half full, it usually sends out nerve signals. These cause the
pelvic floor and sphincter muscles to relax while the detrusor
contracts, squeezing out urine.
In people with OAB, detrusor muscle
contractions occur at random. This leads to a sudden urge to urinate,
even when there's very little urine in the bladder. Depending on how
the urinary sphincter muscles reacts, urine leakage can occur.
Nerve damage and neurocognitive
disorders have long been known to cause OAB symptoms by interfering
with nerve signaling. Some definitions of OAB include neurological
causes. Others refer to the symptoms as the result of nervous system
conditions affecting the bladder. Research is still being conducted
to better understand the role of the nervous system in OAB.
One 2015 study found that the brain of
one person might react to the sensation of the bladder filling
differently to another person. This could mean that treatment options
need to be tailored individually to be effective.
Common OAB causes include: pelvic organ
prolapse, catheter use, stretched or weakened pelvic muscles, low
estrogen levels, especially after menopause, enlarged prostate,
giving birth via the vagina, bladder abnormalities such as bladder
stones or tumors, nerve damage, Parkinson's disease, stroke, and
multiple sclerosis, decreased thinking ability or related diseases,
including Alzheimer's disease, hip surgery or hip problems, stretched
or weakened bladder muscles, incomplete bladder emptying, and
structural problems with the bladder.
While OAB can impact anyone at any age,
the likelihood of developing the condition increases greatly with
age. Despite being so common among older adults, OAB is not simply a
part of aging. If someone's OAB symptoms become severe or disrupt
everyday life, they should see a doctor. Anything that puts excess
weight on or restricts the bladder can increase the risk of
developing OAB.
Activities may also increase the risk
of OAB if they weaken or damage the pelvic floor, urinary, or
sphincter muscles. Conditions that limit the use of pelvic and
abdominal muscles may have the same effect.
The relationship between race and
ethnicity is still unclear. However, one study found higher
prevalence rates of OAB among African American and Hispanic adults
compared with other groups.
Common OAB risk factors include: age,
smoking, being overweight or excess belly fat, gestational diabetes,
pregnancy, frequent or chronic urinary tract infections, long-term
constipation, long-term dehydration or overhydration, chronic
coughing, and medications that cause a clear increase in urination or
fluid intake.
Symptoms -
Though many OAB cases aren't reported, available data indicates
the condition affects a large portion of adults globally. An
estimated 40 percent of American women and 30 percent of American men
are thought to experience OAB symptoms.
At least 30 million American adults
consider their OAB symptoms bothersome to everyday activity. The
direct costs of OAB in the United States are similar to those of
breast cancer and osteoporosis, totaling more than $12 billion
annually.
Most OAB cases are marked by three main
symptoms: urinary urgency, urinary frequency, and urge urinary
incontinence (UUI). Urinary urgency describes a sudden and
uncontrollable desire to urinate even when the bladder isn't full.
In some cases, this urgency can make it difficult to reach a bathroom
in time, leading to UUI.
Urinary frequency describes the need to
urinate an abnormally high amount of times throughout the day and
night. Urinating eight or more times daily without excessive fluid
intake may be a sign of urinary frequency and OAB.
Around half of those with OAB also
experience UUI, or urine leakage. Other common OAB symptoms include
bed-wetting and the need to urinate several times during the night.
OAB tends to affect men and women equally but differences in anatomy
influence aspects of the condition.
A similar proportion of American women
with OAB are estimated to have UUI alongside urgency and frequency.
However, less than 3 percent of American men with OAB report this
combination. Men with OAB may experience higher rates of nocturia
than women.
The physical symptoms of OAB can also
lead to emotional and mental symptoms including depression.
Similarly, fear of an accident, or being far from a bathroom, can
cause social anxiety in those with OAB. In more severe cases, people
with OAB may avoid social situations or change their daily routine
altogether.
Many people with OAB also suffer a loss
of self-esteem and the desire for intimacy. Sleep loss, due to
frequent nighttime urination, is another common symptom of OAB.
Prevention
- Medication and minimally invasive surgery options exist to
treat OAB although the first line of treatment can often be lifestyle
changes.
Many factors like smoking, diet, and
being overweight increase the likelihood of developing OAB and the
severity of symptoms. The lifestyle changes that are recommended for
preventing and managing OAB are essentially the same.
OAB prevention and management options
include: staying hydrated but not overhydrated, losing weight,
treating chronic constipation through medication or diet, pelvic
floor muscle exercises, including Kegels, treating urinary and
bladder infections, quitting smoking to reduce coughing, and regular
exercise.
Many foods and drinks worsen OAB
symptoms. Making a few dietary changes will often reduce symptoms
greatly. Caffeine, alcohol, and salty foods can act as a diuretic,
increasing urine output and trips to the bathroom.
Spicy and acidic foods irritate the
bladder lining, causing discomfort and typically increasing the need
for more bathroom visits. Dehydration also allows bladder irritants
closer contact with the bladder lining, making their effect more
intense.
Foods and drinks to avoid include:
spicy foods, salty foods, caffeinated foods, and drinks such as
coffee, tea, and chocolate, alcohol, items with artificial
sweeteners, acidic foods and drinks, citrus fruits and juices,
tomatoes including juice, whole fruit, and sauces, cranberry juice
and whole fruit, vinegar based products, soda and carbonated drinks,
and MSG.
Onions can also irritate the bladder.
These can be cooked or replaced with shallots to lessen the effect.
Condiments like soy sauce, ketchup, and mustard, are high in salt,
sugar, and acidity. Preservatives in processed foods like takeout
meals and deli meats are also known bladder irritants.
People with severe cases of OAB or
symptoms of the condition may need to treat these suggestions as
rules that they want to adhere to.
To avoid complications, people with
severe OAB are often advised to cook meals at home as much as
possible.
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