One of the major complications of
diabetes is the appearance of wounds in the lower extremities that do
not heal properly. In this situation, a group of researchers from
the UNAM created a solution made of silver nanoparticles, which in
clinical trials has healed ulcers in people with diabetic foot,
avoiding the amputation of more than 90 percent of patients treated.
"The ulcer is an open wound,
susceptible to infection by bacteria and fungi that generate
inflammation, which prevents the injury from healing; however, in
applying the silver nanoparticles an antibacterial effect that
contributes to create healthy tissue," said Dr. Karla Oyuky
Juárez Moreno, researcher at the Center for Nanoscience and
Nanotechnology (CNyN) located in Ensenada, Baja California.
The development, called Nagsil Dermo®
works in three months to heal diabetic foot ulcers. First, a doctor
should remove dead tissue and then apply the solution spray. Dr.
Juarez Moreno stressed that for an effective treatment this must be
applied daily and be supervised by specialists.
According to data from the Ministry of
Health, seven out of ten cases of diabetic foot ulcers result in
amputation and the World Health Organization (WHO) reports that due
to the lack of control of blood glucose, between 40 and 85 percent of
patients lose a limb.
The solution applied in patients that
had a treatment with antibiotic during more than six months but don't
see improvements, some had the diagnostic of amputation. "With
our development report of a cicatrization, the time depends on the
ulcer.
Four types of vascular damage and
tissue exist. "Those who have the levels one, two and three
relieved in less of six months, therefore those which have the level
four where the amputation is inevitable, in this cases there is a ten
percent of success," detailed Dr. Juarez Moreno.
The group of scientists has implemented
innovation in private clinics and health sector, including ISSSTECALI
hospitals and General de Rosarito, both located in Baja California,
in the latter over a hundred cases were treated and 94 percent saved
their limbs.
At national level there are 60 patients
who have saved their limbs from the use of Nagsil Dermo®, an
economic cosmetic product whose price is 550 pesos for a bottle of 50
milliliters, which is marketed through Bionag, a spin off created by
the Network Conacyt located in Tijuana.
Scientific and technological
development has international certificates toxicity committees
supporting the safety of silver nanoparticles for use as a cosmetic
in humans. They are also coated with a polymer that provides
stability for more than two years.
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