July 19, 2013

New AACE Diabetes Algorithm Consensus Statement

Well, finally the criticism has forced the American Association of Clinical Endocrinologists (AACE) into action. They have now issued a new type 2 diabetes algorithms consensus statement to accompany the original algorithms. This consensus statement is 48 pages in length and is available for free download. Yes, again, it is in the PDF format and the original 8 pages of the diabetes algorithms are turned on their side to make them more difficult to read.

Now I must ask, did the criticism finally bring them to their senses? It may have, plus the blogger gnats may have become pesky enough. I think that Dr. Anne Peters and
Dr. Jerry Avorn articles convinced them to do more. What is important is the disclosure of the ties to Big Pharma including for Dr. Alan J Garber, who has some rather substantial conflicts of interest. These disclosures start on page 29 and while are not surprising, do show how tied to the drug companies most of the people are. This is just one more reason to be cautious about relying on the AACE diabetes algorithms.

What I find upsetting is the continued reference to the benefits of weight loss surgery or bariatric surgery as being the recommendation of preference. We know that this is not the cure-all claimed and many people are not able to maintain the strict diet required for bariatric surgery to be successful in the long term. The references chosen of course do not include the discussion in this Medical News Today article which emphasizes following the diet recommended for those that have bariatric surgery and receiving many if not most of the benefits.

I find the prediabetes section almost insulting as they say the primary goal of prediabetes management is weight loss as if everyone with prediabetes is overweight. I have met many patients with prediabetes that are not overweight. They continue that, when indicated, bariatric surgery can also be highly effective in preventing progression to diabetes. At least they felt obligated to say, weight loss may not directly address the pathogenesis of declining beta-cell function.

I am very surprised that no mention is made of medications being used “off label” because at present the FDA does not list any approved oral diabetes medications for prediabetes. Because metformin and acarbose are generic and relatively inexpensive to purchase, I can accept this. However, I think it would be wise for the drug manufacturers that the American Diabetes Association (ADA) and the AACE support with their dogma to have these approved. There are several other medications promoted in the Consensus that also should be on the approved list of drugs before they are used “off label.” These currently have FDA warnings, but AACE does not want the patient to know of them.

The AACE Diabetes Algorithms consensus statement is consistent in their promotion of weight loss and bariatric surgery as often the best option. They are also consistent in making readers aware of preventing hypoglycemia as a priority.

As I have time to study the consensus statement further, I will blog about it and I am hoping to see other professionals making statements about the consensus statement.

July 18, 2013

Joslin SEEMS a Fan of AACE Algorithm

It seems that we are going to be continually bombarded with the American Association of Clinical Endocrinologists (AACE) Diabetes Algorithms. This time it is the Joslin Diabetes Center trumpeting the algorithms. The author of the Joslin blog tells us what we know and that is that the algorithms are for practitioners, both the endocrinologists and primary care physicians (PCPs). And yes, most people with diabetes are cared for by a primary care physicians, but that means they will have one diabetes medication stacked on another.

If things hold true, many of the diabetes patients will be kept on oral medications for too long a time as A1c's rise. The algorithms recommend moving to insulin, but many PCPs are very hesitant to move diabetes patients to insulin because they are also afraid of hypoglycemia.

I admit that the following statement by the Joslin blog author has me concerned and wondering why they are agreeing that diabetes is progressive. “They also place greater emphasis on the use of medication early in the pre-diabetes stage of the disease. Including medications as a concomitant part of treatment from the beginning, acknowledges both the difficulty of lifestyle therapy and the progressive nature of the disease.” This disagrees with the statement of Dr. Anne Peters from the University of Southern California, “The authors have eliminated hemoglobin A1c as part of the diagnostic criteria for prediabetes and don't describe in much detail how to decide when to treat somebody with prediabetes. There is no current US Food and Drug Administration-approved medication for the treatment of prediabetes.”

This tells me that Joslin is not afraid to use diabetes medications “off label” and with metformin being economical, this may be acceptable, as most insurance companies will not reimburse for pre-diabetes medications. The fact that Joslin considers diabetes progressive should concern every patient at Joslin, and especially if you are working to prevent progression to complications.

Joslin also apparently follows the American Diabetes Association guideline of 7% as the ideal A1c level and this also indicates that they consider diabetes progressive and that there is no means to prevent this – how very depressing. I can agree with the statement that A1c needs to be individualized for the elderly that are having other disease or comorbid problems, but they don't say this. They only say the target A1c needs modification based on individual risk factors and circumstances. Then the blog concludes with the statement, “Prevention of hypoglycemia is paramount when developing a treatment strategy for patients.”

There are so many issues left unsaid and others that are hinted at, that one needs to wonder who sets policies at Joslin and then if anyone follows these policies, if any exist. In the last few months, more conflicting comments have appeared in Joslin's blogs and in other sources. Then they refuse to identify the person writing the blog by saying the blog is by Joslin Communications.

July 17, 2013

What Is A Person With Type 2 to Do? - Part 2

Part 2 of 2 parts

It is amazing the number of problems that we as type 2 patients face to learn about diabetes and how to care for ourselves. Is it any wonder many people give up and become depressed? I can understand this and try as I might, the only answer I can find is to self-educate ourselves. Yes, some can find excellent doctors, certified diabetes educators, and excellent nutritionists, (no I did not say dietitians), and excellent support groups. If you have one of these people, work very hard to keep them, respect them, and learn from them. We will all probably need to continually battle our high profit minded insurance companies for medicines and testing supplies, but this is a battle all must fight.

I am fortunate to be part of a very strong diabetes support group. Activities are slowing for the summer, but I know several people are paying attention to the FDA discussion on Avandia and several of the other diabetes drugs. Self-education is a tool we work at together, we inform each other about different studies and research that is published online, and we often talk about them by exchanging emails and occasionally using video conferences.

We as a group are thankful that we are able to talk about diabetes and while we know of some people that are outside of the group that will not talk about diabetes and are doing their best to keep it a secret, this is not a goal of any of the current members. With diabetes being the 24/7 problem, we will accept support from each other and be glad that we have this. There are three that are not members, but they do talk to different members quite frequently and we help them when asked. We know why they do not want to be members at this time and we are not pushing them to join. Two are just happy that we thought enough of them to include them on our email list. Their jobs keep them busy and away from home to the point that when they are home, they wish to spend time with their family. The third is talking to Brenda and me, but there are other factors involved as well.

I will again list several of my blogs for people to review and hopefully find information that will help them learn and become knowledgeable about diabetes. Blog 1, blog 2, and blog 3 contain information and websites to read and explore.  There is some duplication between blog 1 and blog 3.

Because many of us do not have doctors that have time to educate us, certified diabetes educators available, or facilities available to assist in diabetes education, it is our responsibility to educate ourselves. Some doctors will encourage this and others will not. The doctors that will not, often feel they are all that you need and do not want you on the internet educating yourself. So be careful and do not bring lots of printed materials to an appointment with these doctors. You would be better served by asking how they feel about you finding information on the internet. If they discourage this, then by all means use the internet and keep quiet about it. Local libraries can sometimes be useful in finding books or using their computers. Therefore, do not be discouraged if you do not own a computer.

Another resource person you may be able to use for medications is your pharmacist. Some are very helpful and again others do not feel they should help. This will often depend on how busy the pharmacist is.

July 16, 2013

What Is A Person With Type 2 to Do?

Part 1 of 2 parts

This is a topic that is a torment to put in words, but I must. I see the world of diabetes care being slowly torn apart by several people in the medical field who are or have been in high positions for the American Diabetes Association (ADA) and the American Association of Clinical Endocrinologists (AACE). That is the primary reason for writing this blog about the two doctors.

One feels that as a person with type 2 diabetes and not on insulin, you should not test, but be satisfied with your quarterly A1c test results. What he fails to say is that many primary care physicians only test type 2 patients once or twice a year. What is a patient with type 2 diabetes on oral medications to do? The view of this doctor is completely out of touch with reality. Maybe this is what working as a Professor of Medicine at Georgetown University Medical School and Senior Research Scientist at the MedStar Health Research Institute in metropolitan Washington, DC does to you.

The other doctor also is a Professor of Medicine, Biochemistry & Molecular Biology, and Molecular & Cellular Biology at Baylor College of Medicine, Houston, Texas. Only this doctor wants to put you in a medical straight jacket and force you to do what he wants and how he wants you to mind the doctor's orders. This is the reason behind writing this blog on the Diabetes Algorithms and this blog on criticism of the Algorithm.

I admit I have respect for other professors of medicine, even when we disagree about issues, for example, Dr. Matthew Mintz. I did one blog very favorable about what he and another doctor have said about diabetes patients, yet I can disagree with his stand in favor of Avandia in his blog here. He has disclosed his conflict of interest and is willing to talk about a variety of topics, but he is not saying this is what it has to be in his discussion of Avandia.

How is the patient that wishes to prevent diabetes from becoming progressive even going to learn how to manage diabetes? One doctor only wants the patient to rely on A1c tests and the other only to follow precise doctor orders. We all should know that in the real world, the one that these doctors don't live in obviously, the patient is the one needing to learn to manage diabetes. Their doctor cannot be with them 24/7/365. How else will the patient be able to take ownership of their diabetes?

Then the other battle people with type 2 diabetes continually face is obtaining enough testing supplies to learn how the different foods and daily exercise affects his/her blood glucose levels. Our medical insurance companies listen to the “expert” medical professionals and their associations and will not cover the number of test strips people need shortly after diagnosis. Even the study I blogged about here is not receiving much attention or creditability by the profit greedy insurance companies.

Two other diabetes related professions make it difficult for patients to receive education and learn how to manage their diabetes. The first is the Academy for Nutrition and Dietetics (AND) which is lobbying the states to make them the only profession to be able to teach nutrition, and then goes out and criminalizes other nutritionists that are actually teaching nutrition. The AND is a front for Big Food and promotes what they sell. Instead of assessing the patient for nutrition, we are told to eat so many calories and carbohydrates, balanced or unbalanced nutritionally, that many are unable to manage their diabetes and it becomes progressive, and the complications become a fact of life. Now they are lobbying at the federal level to expand their monopoly and become the most acceptable organization to counsel people with obesity. If this organization is allowed their way, our choices for obtaining dietary information will be extremely limited and again we, as patients, will suffer.

The second organization is the American Association of Diabetes Educators (AADE). The AADE is so enamored with their amount of education (sic) that they will not consider creating a group of peer mentors or peer-to-peer workers to help educate people with type 2 diabetes. The AADE claims a membership of 13,000, but many of their members are retired, writing books and going on speaking tours, working for organizations that are not doing education, or only work part-time, that they probably have fewer that 5,000 full-time certified diabetes educators (CDEs). The sad part of these people is there is so much that they need to learn that many do not know how to correctly assess patients and match their needs. In addition, but with a few exceptions, most CDEs will not deal with depression, sleep apnea, and others of the comorbid conditions of diabetes patients. Many find it easier to use mandates, mantras, and dogma instead of good education when dealing with type 2 patients.

Thankfully, some doctors are seeing the need and working with knowledgeable patients to give them the extra education to work as peer-to-peer workers. Some doctors in largely rural areas are working with peer mentors and using video conferences for education.

Because the current medical system is so time constrictive for doctors, many people that do realize the need for education are left with the internet for education. Fortunately, some find the good websites and then realize that there are many poor websites for diabetes information. Yet many patients fall victim to the “snake-oil” salespeople that do nothing but separate them from their money. Is it any wonder they become embittered with the system.

With the ADA and AACE beholden to Big Pharma, the AND in bed with Big Food, the AADE believing only they, with their exclusive education should be the source of it, and the internet riddled with poor information, where do people with type 2 diabetes turn?

Before leaving this and listing some solutions, one more weakness needs to be reemphasized. The weakness is diabetes research for type 2 which discriminates against the elderly and the young. This means for the largest segment of the type 2 diabetes population, there is almost no clinical research that doctors can rely on for treatment of the elderly. This causes doctors and even endocrinologists to experiment on us as patients. Some do very well and others leave much to be desired. Even the diabetes algorithms cannot cover this with certainty.

The next blog will discuss some possible solutions.

July 15, 2013

HbA1c Not Adequate to Assess Diabetes Care

Is the measure of HbA1c really inadequate in assessing diabetes care across specialties? According to this presentation at the American Diabetes Association 2013 Scientific Sessions, HbA1c levels for patients cared for by endocrinologists are the same as or better than those for individuals seen by general internists.

Why is this a big deal? Because when patients are compared on a medication basis, the general internists generally held their own except when it came to insulin where the general internists came out ahead. The study authors concluded that this was because primary care physicians were referring these patients to endocrinologists. Then the authors state that this was the reason endocrinologists were seeing patients with higher HbA1c levels. This is the reason the study authors do not believe that HbA1c is an adequate measure and does not allow for an apples-to-apples comparison.

This may be true, but without an age comparison, can we really be confident that the study authors are not concealing something. With the pressure I am receiving to bring my A1c levels up, we know that when we are discussing insulin, that the endocrinologists are fearful of hypoglycemia and in many ways let age govern their individualization instead of individual capabilities. Even a couple of other members of our support group are feeling the pressure to allow their A1c levels to increase.

This article in Medscape states that more elderly are admitted to hospitals for hypoglycemia than hyperglycemia. Unless I missed something, in neither article do they distinguish between types 1 nor type 2 and which may be causing the problems and the conclusions they are drawing. To properly evaluate the statistics in the hypoglycemia and in the study wanting to compare apples-to-apples, without numbers of each type being reported, the results can be misleading.

The apples-to-apples study was generally about type 2 patients, except that type 1 is mentioned here, “Those also using mealtime insulin in addition to basal insulin, with or without other medications (1531). The latter group included patients with type 1 diabetes, Dr. Phillips told Medscape Medical News.” This is where the confusion comes in and we are left wondering which type they are worried about causing the HbA1c problems and preventing the apples-to-apples comparison.

This is probably the reason for this statement - “This coverage is not sanctioned by, nor a part of, the American Diabetes Association.” This I know means that the study has not been peer-reviewed and could be the reason for poor information.